STEAP4 antibody

Catalog No. ABIN7119515

The Rabbit Polyclonal anti-STEAP4 antibody has been validated for ELISA, IHC, WB and IP. It is suitable to detect STEAP4 in samples from Human, Mouse and Rat.

Quick Overview for STEAP4 antibody (ABIN7119515)

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STEAP4 Antibody

Purpose: STEAP4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: STEAP family member 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for STEAP4

Target: STEAP4 (STEAP Family Member 4 (STEAP4))

Alternative Name: STEAP4

Background:

Synonyms: Metalloreductase STEAP4|Six-transmembrane epithelial antigen of prostate 4|SixTransMembrane protein of prostate 2|Tumor necrosis factor, alpha-induced protein 9|STEAP4|STAMP2|TNFAIP9

Background: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses(By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.

Molecular Weight: 52 kDa

Gene ID: 79689

UniProt: Q687X5

Pathways: Transition Metal Ion Homeostasis